Burkitt Lymphoma: A Review
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چکیده
Burkitt Lymphoma (BL) is a high grade Non-Hodgkins Lymphoma (NHL) that is characterized histopathologically by a mass of diffuse small non-cleaved B cell lymphocytes [1,2]. It is a highly aggressive lymphoma that frequently presents in extranodal sites with a very high proliferation rate. It is the fastest growing tumour, characterized by explosive growth with a doubling time of 24 hours. BL is of greatest importance in sub-Saharan Africa where it is the most common childhood (2-16 years, mean 7 years) cancer, accounting for up to 36% of childhood cancers and 70% of childhood lymphomas [3] but, overall constitutes 5% of lymphomas for both adult and childhood populations.
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